Machine intelligence
Google is at the forefront of innovation in Machine Intelligence, with active research exploring virtually all aspects of machine learning, including deep learning and more classical algorithms. Exploring theory as well as application, much of our work on language, speech, translation, visual processing, ranking and prediction relies on Machine Intelligence. In all of those tasks and many others, we gather large volumes of direct or indirect evidence of relationships of interest, applying learning algorithms to understand and generalize.
Machine Intelligence at Google raises deep scientific and engineering challenges, allowing us to contribute to the broader academic research community through technical talks and publications in major conferences and journals. Contrary to much of current theory and practice, the statistics of the data we observe shifts rapidly, the features of interest change as well, and the volume of data often requires enormous computation capacity. When learning systems are placed at the core of interactive services in a fast changing and sometimes adversarial environment, combinations of techniques including deep learning and statistical models need to be combined with ideas from control and game theory.
Recent Publications
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The field of Human-Computer Interaction is approaching a critical inflection point, moving beyond the era of static, deterministic systems into a new age of self-evolving systems. We introduce the concept of Adaptive generative interfaces that move beyond static artifacts to autonomously expand their own feature sets at runtime. Rather than relying on fixed layouts, these systems utilize generative methods to morph and grow in real-time based on a user’s immediate intent. The system operates through three core mechanisms: Directed synthesis (generating new features from direct commands), Inferred synthesis (generating new features for unmet needs via inferred commands), and Real-time adaptation (dynamically restructuring the interface's visual and functional properties at runtime). To empirically validate this paradigm, we executed a within-subject (repeated measures) comparative study (N=72) utilizing 'Penny,' a digital banking prototype. The experimental design employed a counterbalanced Latin Square approach to mitigate order effects, such as learning bias and fatigue, while comparing Deterministic interfaces baseline against an Adaptive generative interfaces. Participant performance was verified through objective screen-capture evidence, with perceived usability quantified using the industry-standard System Usability Scale (SUS). The results demonstrated a profound shift in user experience: the Adaptive generative version achieved a System Usability Scale (SUS) score of 84.38 ('Excellent'), significantly outperforming the Deterministic version’s score of 53.96 ('Poor'). With a statistically significant mean difference of 30.42 points (p < 0.0001) and a large effect size (d=1.04), these findings confirm that reducing 'navigation tax' through adaptive generative interfaces directly correlates with a substantial increase in perceived usability. We conclude that deterministic interfaces are no longer sufficient to manage the complexity of modern workflows. The future of software lies not in a fixed set of pre-shipped features, but in dynamic capability sets that grow, adapt, and restructure themselves in real-time to meet the specific intent of the user. This paradigm shift necessitates a fundamental transformation in product development, requiring designers to transcend traditional, linear workflows and evolve into 'System Builders'—architects of the design principles and rules that facilitate this new age of self-evolving software.
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MoXaRt: Audio-Visual Object-Guided Sound Interaction for XR
Sieun Kim
Qianhui Zheng
Ruoyu Xu
Ravi Tejasvi
Anuva Kulkarni
Junyi Zhu
2026
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In Extended Reality (XR), complex acoustic environments often overwhelm users, compromising both scene awareness and social engagement due to entangled sound sources. We introduce MoXaRt, a real-time XR system that uses audio-visual cues to separate these sources and enable fine-grained sound interaction. MoXaRt's core is a cascaded architecture that performs coarse, audio-only separation in parallel with visual detection of sources (e.g. faces, instruments). These visual anchors then guide refinement networks to isolate individual sources, separating complex mixes of up to five concurrent sources (e.g. two voices + three instruments) with ca. 2 second processing latency. We validate MoXaRt through a technical evaluation on a new, complex dataset we collected, and a 22-participant user study. Our results demonstrate that MoXaRt significantly improves communication clarity—boosting listening comprehension in noisy conditions by 33.2% (p=0.0058)—and significantly reduces cognitive load (M=7.50 vs. M=3.36, p<0.001), paving the way for more perceptive and socially adept XR experiences.
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Towards Conversational AI for Disease Management
Khaled Saab
David Stutz
Yong Cheng
Kavita Kulkarni
Sara Mahdavi
Joelle Barral
James Manyika
Ryutaro Tanno
Adam Rodman
Nature (2026)
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While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain under-explored. We advance the previously demonstrated diagnostic capabilities of the Articulate Medical Intelligence Explorer (AMIE) through a new LLM-based agentic system optimised for clinical management and dialogue, incorporating reasoning over the evolution of disease and multiple patient visit encounters, response to therapy, and professional competence in medication prescription. To ground its reasoning in authoritative clinical knowledge, AMIE leverages Gemini's long-context capabilities, combining in-context retrieval with structured reasoning to align its output with relevant and up-to-date clinical practice guidelines and drug formularies. In a randomized, blinded virtual Objective Structured Clinical Examination (OSCE) study, AMIE was compared to 21 primary care physicians (PCPs) across 100 multi-visit case scenarios designed to reflect UK NICE Guidance and BMJ Best Practice guidelines. AMIE was non-inferior to PCPs in management reasoning as assessed by specialist physicians and scored better in both preciseness of treatments and investigations, and in its alignment with and grounding of management plans in clinical guidelines. To benchmark medication reasoning, we developed RxQA, a multiple-choice question benchmark derived from two national drug formularies (US, UK) and validated by board-certified pharmacists. While AMIE and PCPs both benefited from the ability to access external drug information, AMIE outperformed PCPs on higher difficulty questions. While further research would be needed before real-world translation, AMIE's strong performance across evaluations marks a significant step towards conversational AI as a tool in disease management.
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The Ontic-Epistemic Distinction: Implications for General Intelligence
Master's Thesis (2026) (to appear)
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The current pursuit of robust machine intelligence is largely predicated on a substrate independent, computational functionalist view of cognition, where sufficiently complex computational processing is expected to eventually yield generalized reasoning. This paper explores the ontological distinctions between these computational frameworks and biological cognition, specifically how these differences impact the capacity for semantic understanding. By analyzing phenomena such as the "reversal curse" where models fail to generalize the symmetry in identity relations (A=B implies B=A), and performance on novel reasoning benchmarks (e.g., ARC-AGI), this paper examines whether current model limitations are transient artifacts of scale or indicative of a distinct architectural category. Integrating Stevan Harnad’s “symbol grounding problem” with Evan Thompson’s biological model of “intrinsic normativity,” I investigate whether robust general intelligence might require sense-making: a process distinct from information processing, whereby an agent’s internal states are causally coupled with its environment via survival or system-wide stakes which grounds symbols in meaning. Current Large Language Models (LLMs) appear to lack this intrinsic normativity, and consequently may operate primarily as epistemic instruments rather than ontic agents. By introducing the concept of “ontic grounding”, this paper presents a potential framework for distinguishing between the simulation of reasoning and true understanding, which could have implications for AI safety and governance.
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Validating conversational artificial intelligence (AI) for regulated medical software applications may present challenges, as static test datasets and manual review may be limited in identifying emergent, conversational anomalies. A multi-agent AI system may be configured in a closed-loop for automated validation. The system can, for example, utilize an end user persona simulator agent to generate prompts for a target model and a domain /regulatory expert adjudicator agent to evaluate the target model’s responses against a configurable rubric. A meta-analysis agent can analyze anomalies to identify underlying vulnerabilities, which may then be used to programmatically synthesize new adversarial personas. This adaptive process can generate evidence to support regulatory compliance and continuous performance monitoring for medical software algorithms systems.
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Automating AI research differs from general software engineering due to computationally expensive evaluation (e.g., model training) and opaque performance attribution. Current LLM-based agents struggle here, often generating monolithic scripts that ignore execution costs and causal factors. We introduce MARS (Modular Agent with Reflective Search), a framework optimized for autonomous AI research. MARS relies on three pillars: (1) Budget-Aware Planning via cost-constrained Monte Carlo Tree Search (MCTS) to explicitly balance performance with execution expense; (2) Modular Construction, employing a "Design-Decompose-Implement" pipeline to manage complex research repositories; and (3) Comparative Reflective Memory, which addresses credit assignment by analyzing solution differences to distill high-signal insights. MARS achieves state-of-the-art performance among open-source frameworks on MLE-Bench under comparable settings, maintaining competitiveness with the global leaderboard's top methods. Furthermore, the system exhibits qualitative "Aha!" moments, where 63% of all utilized lessons originate from cross-branch transfer, demonstrating that the agent effectively generalizes insights across search paths.
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